Clue: Sir Isaac
Sir Isaac is a crossword puzzle clue that we have spotted 4 times. There are related clues (shown below).
Referring crossword puzzle answers
Likely related crossword puzzle clues
Recent usage in crossword puzzles:
- Sheffer - Oct. 6, 2017
- New York Times - Aug. 8, 1994
- New York Times - May 24, 1987
- New York Times - March 20, 1973